According to Drugs in Pregnancy and Lactation5, both tramadol and its pharmacologic lively metabolite (O-desmethyltramadol) are excreted into human milk. Thus, ingestion of the recommended dose may produce drug quantities in breast milk that could exceed those reported above. One non-fatal U.S. case concerned a 6-year-old who was prescribed tramadol for neuropathy of the hands…
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